Ophthalmoscopic findings in subacute sclerosing panencephalitis.

Ophthalmoscopic findings in subacute sclerosing panencephalitis.

Subacute sclerosing panencephalitis (SSPE) is a progressive central nervous system disorder affecting both grey and white matter; it affects children and young adults and, with only occasional exceptions, is fatal. Present interest in the illness stems from the observation that the disease is due to a slow virus infection produced by measles or a measles-like virus (Horta-Barbo-a, Fuccillo, and...

Subacute Sclerosing Panencephalitis, immunological findings in saliva and salivary glands

Subacute Sclerosing Panencephalitis in Iran

[Subacute sclerosing panencephalitis].

Subacute sclerosing panencephalitis is a slowly progressive neurodegenerative disorder occurring in childhood and adolescence and is characterised by dementia, ataxia, myoclonias and other neurological focal signs, with an invariably fatal outcome. The author reviews the subject, focussing on epidemiology, clinical features, measles virus behaviour, host immune reactions, measles prophylaxis an...

Subacute sclerosing panencephalitis.

Introduction Subacute sclerosing panencephalitis (SSPE) is a rare disease which predominantly affects children of school age. The clinical features include an insidious afebrile onset with behavioural disturbance and progressive dementia sometimes associated with epilepsy. Later akinetic mutism and myoclonic jerks with pyramidal and extrapyramidal signs appear. Finally there is progressive deco...